The latest scare has just as many complications as in the past, including all the pitfalls of the petri dish extrapolations discussed above. 15 Furthermore, in a recent webinar with essential oil expert, Robert Tisserand, it was pointed out that the petri dish trays themselves contain plasticizers – known endocrine disruptors – that could be further broken down by the essential oils, released into the medium, and cause endocrine disruption that is mistakenly attributed to the essential oils or their constituents. DMSO also has been reported to alter outcomes in experiments via stimulation or inhibition of steroid signaling, depending on dosage used. (Please refer to my essential oils database 14 for articles about quality measurements of essential oils, as this is beyond the scope of this current discussion). In the in-vitro experiment, the oils “were diluted in dimethylsulfoxide before they were added to culture media.” 6 This is not in alignment with conserving essential oils’ delicate constituents and their medicinal properties. 6,12,13 This disregards the synergy of pure essential oils – a concept that will be discussed in more detail later as it relates to the most recent study. The lavender tested in vitro was likely attained from a synthetic source, according to the supplier listed in the article. 7Īnother problem was that the essential oils within the products were not validated for therapeutic quality and sourcing. The dosages used to produce the effects in a petri dish in the experiment were also likely not generalizable to actual human absorption of these oils in a commercial product. 6,10,11 This biases the inference of sex-steroid alterations by the essential oils. These consumer goods are known to have ingredients that are deemed to be endocrine disruptors. First, the cases in question were not connected to the use of the pure essential oils of lavender and tea tree rather, all of them were linked to personal care products that contained these oils. 6-8įor several reasons, this 2007 study has been criticized for its conclusions. 6 The sex-steroid signaling disturbances were “verified” by an in-vitro analysis of human breast cancer (MCF-7) cells that express estrogen receptors as well as human breast cancer (MDA-kb2) cells that express the androgen receptor. The New England Journal of Medicine published an article in 2007 that reported on 3 cases of prepubertal gynecomastia associated with lavender and tea tree essential oils. Ramsey said these changes were consistent with endogenous, or bodily, hormonal conditions that stimulate gynecomastia in prepubescent boys. Using in vitro, or test tube, experiments, the researchers applied these chemicals to human cancer cells to measure changes of estrogen receptor- and androgen receptor-target genes and transcriptional activity.Īll eight chemicals demonstrated varying estrogenic and/or anti-androgenic properties, with some showing high or little to no activity, the investigators reported. The others were in either oil: linalyl acetate, linalool, alpha-terpinene and gamma-terpinene. Four of the tested chemicals appear in both oils: eucalyptol, 4-terpineol, dipentene/limonene and alpha-terpineol. From the hundreds of chemicals that comprise lavender and tea tree oil, they selected for analysis eight components that are common and mandated for inclusion in the oils. Under Korach’s direction, Ramsey and his NIEHS colleagues went a step further. The methods of the experiment were highlighted in Science Daily 5: The media then deemed these essential oils to be endocrine disruptors that could cause young boys to develop gynecomastia. Because the in-vivo results indicated changes in the cellular gene activities of estrogen and androgen receptors, they concluded that the synergistic, therapeutic essential oils might behave similarly in vivo. 4 In the study, the researchers assessed the hormonal effects of 8 constituents commonly found in lavender and tea tree essential oils on human cancer cells. 1-5 The uproar stemmed from findings presented at the Endocrine Society’s 100th annual meeting and released in March 2018. The controversy over the “estrogenic properties” of certain essential oils resurfaced recently, sending essential oil lovers and the media into a familiar state of confusion. You may also use the search box to search for members by name or office.For the love of science, can we stop the chit-chat about lavender, tea tree, and man boobs in little boys?! This list includes both REALTOR® real estate brokers and REALTOR® appraisers. NOTE: To view a roster of all REALTOR® members within a specific office, simply select the desired office from the drop-down list. Housing Statistics (Year-to-Date Report).
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